Assay Detail
Binding
CHEMBL1664680
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Shp1
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 6 (CHEMBL3166) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.17 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1650889 | — | — | 1 | 6.47 |
| CHEMBL1650891 | — | — | 1 | 6.42 |
| CHEMBL1650892 | — | — | 1 | 6.39 |
| CHEMBL1650893 | — | — | 1 | 6.31 |
| CHEMBL1650918 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1650889 | — | IC50 | = | 335.0 | nM | 6.47 |
| CHEMBL1650891 | — | IC50 | = | 378.0 | nM | 6.42 |
| CHEMBL1650892 | — | IC50 | = | 408.0 | nM | 6.39 |
| CHEMBL1650893 | — | IC50 | = | 486.0 | nM | 6.31 |
| CHEMBL1650918 | — | IC50 | = | 5760.0 | nM | 5.24 |