Assay Detail
Binding
CHEMBL1670073
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Binding affinity to human galectin-3 by surface plasmon resonance method
17
Total Activities
5
Compounds Tested
4
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and galectin-binding activities of mercaptododecyl glycosides containing a terminal β-galactosyl group.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 5.82 | 5.97 |
| Activity | 5 | - | - |
| Kdiss | 3 | - | - |
| Ka | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1669628 | — | — | 5 | 5.97 |
| CHEMBL1669630 | — | — | 5 | 5.84 |
| CHEMBL1669631 | — | — | 5 | 5.66 |
| CHEMBL1669629 | — | — | 1 | - |
| CHEMBL1669627 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1669628 | — | Kd | = | 1060.0 | nM | 5.97 |
| CHEMBL1669628 | — | Kd | = | 1060.0 | nM | 5.97 |
| CHEMBL1669630 | — | Kd | = | 1430.0 | nM | 5.84 |
| CHEMBL1669630 | — | Kd | = | 1430.0 | nM | 5.84 |
| CHEMBL1669631 | — | Kd | = | 2200.0 | nM | 5.66 |
| CHEMBL1669631 | — | Kd | = | 2200.0 | nM | 5.66 |
| CHEMBL1669631 | — | Activity | = | 166.9 | a.u. | - |
| CHEMBL1669630 | — | Activity | = | 135.1 | a.u. | - |
| CHEMBL1669629 | — | Activity | = | 5.1 | a.u. | - |
| CHEMBL1669628 | — | Activity | = | 82.3 | a.u. | - |
| CHEMBL1669627 | — | Activity | - | — | - | |
| CHEMBL1669628 | — | Kdiss | = | 1.86 | 10'-3/s | - |
| CHEMBL1669628 | — | Ka | = | 1760.0 | 1/M.sec | - |
| CHEMBL1669631 | — | Ka | = | 5670.0 | 1/M.sec | - |
| CHEMBL1669630 | — | Kdiss | = | 2.72 | 10'-3/s | - |
| CHEMBL1669631 | — | Kdiss | = | 1.25 | 10'-2/s | - |
| CHEMBL1669630 | — | Ka | = | 1900.0 | 1/M.sec | - |