Assay Detail
Binding
CHEMBL1670271
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Ratio of Ki for rat MT1 to Ki for rat MT2
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ratio Ki | 2 | - | - |
| Ki | 1 | 8.25 | 8.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1669700 | — | — | 1 | 8.25 |
| CHEMBL1669704 | — | — | 1 | - |
| CHEMBL1669685 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1669700 | — | Ki | = | 5.6 | nM | 8.25 |
| CHEMBL1669704 | — | Ratio Ki | = | 4.0 | — | - |
| CHEMBL1669685 | — | Ratio Ki | = | 4.0 | — | - |