Assay Detail
Binding
CHEMBL1670626
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Inhibition of Saccharomyces cerevisiae FTase after 15 mins by fluorimetric analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.77 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1668041 | — | — | 1 | 7.77 |
| CHEMBL1668039 | — | — | 1 | 7.39 |
| CHEMBL1667866 | — | — | 1 | 6.51 |
| CHEMBL1214486 | ORHALQUINONE | — | 1 | 6.40 |
| CHEMBL513747 | HELENAQUINONE | — | 1 | 5.80 |
| CHEMBL1668040 | — | — | 1 | - |
| CHEMBL1668042 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1668041 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL1668039 | — | IC50 | = | 41.0 | nM | 7.39 |
| CHEMBL1667866 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL1214486 | ORHALQUINONE | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL513747 | HELENAQUINONE | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL1668040 | — | IC50 | - | — | - | |
| CHEMBL1668042 | — | IC50 | - | — | - |