Assay Detail
Functional
CHEMBL1670628
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Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum FcB1 after 48 hrs
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.98 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1668041 | — | — | 1 | 6.21 |
| CHEMBL1667866 | — | — | 1 | 5.06 |
| CHEMBL1214486 | ORHALQUINONE | — | 1 | 5.04 |
| CHEMBL1668039 | — | — | 1 | 5.04 |
| CHEMBL1668040 | — | — | 1 | 4.28 |
| CHEMBL1668042 | — | — | 1 | 4.25 |
| CHEMBL513747 | HELENAQUINONE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1668041 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL1667866 | — | IC50 | = | 8800.0 | nM | 5.06 |
| CHEMBL1214486 | ORHALQUINONE | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL1668039 | — | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL1668040 | — | IC50 | = | 52800.0 | nM | 4.28 |
| CHEMBL1668042 | — | IC50 | = | 55800.0 | nM | 4.25 |
| CHEMBL513747 | HELENAQUINONE | IC50 | > | 30000.0 | nM | - |