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Assay Detail

CHEMBL1670666

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]-angiotensin 2 from angiotensin AT1 receptor in bovine adrenal cortical membranes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Type-1 angiotensin II receptor (CHEMBL3374)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
Naik P, Murumkar P, Giridhar R, Yadav MR.
Bioorg Med Chem (2010) 18 : 8418 -8456
PubMed 21071232 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.26 6.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL48242 1 6.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL48242 IC50 = 550.0 nM 6.26