Assay Detail

CHEMBL1670669

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Binding

Binding affinity to angiotensin AT1 receptor in rat lung membranes

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Rattus norvegicus
Tissue	Lung
Subcellular	Membrane
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.

Naik P, Murumkar P, Giridhar R, Yadav MR.
Bioorg Med Chem (2010) 18 : 8418 -8456
PubMed 21071232 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	8.43	8.43

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1017	TELMISARTAN	4.0	1	8.43

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1017	TELMISARTAN	Ki	=	3.7	nM	8.43