Assay Detail
Binding
CHEMBL1670939
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Inhibition of Aeromonas proteolytica aminopeptidase by Dixon plot analysis
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Vibrio proteolyticus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Amino-benzosuberone: a novel warhead for selective inhibition of human aminopeptidase-N/CD13.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.81 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29292 | UBENIMEX | 2.0 | 1 | 8.80 |
| CHEMBL1668628 | — | — | 1 | 4.82 |
| CHEMBL1668623 | — | — | 1 | - |
| CHEMBL1668624 | — | — | 1 | - |
| CHEMBL1668625 | — | — | 1 | - |
| CHEMBL1668626 | — | — | 1 | - |
| CHEMBL1668627 | 2-AMINOCYCLOHEPTANONE HYDROCHLORIDE | — | 1 | - |
| CHEMBL1668629 | — | — | 1 | - |
| CHEMBL1668630 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29292 | UBENIMEX | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL1668628 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1668623 | — | IC50 | = | 130000.0 | nM | - |
| CHEMBL1668624 | — | IC50 | = | 150000.0 | nM | - |
| CHEMBL1668625 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL1668626 | — | IC50 | = | 900000.0 | nM | - |
| CHEMBL1668627 | 2-AMINOCYCLOHEPTANONE HYDROCHLORIDE | IC50 | = | 350000.0 | nM | - |
| CHEMBL1668629 | — | IC50 | - | — | - | |
| CHEMBL1668630 | — | IC50 | > | 1000000.0 | nM | - |