Assay Detail
Functional
CHEMBL1673569
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Ratio of EC50 Hepatitis C virus in presence of 1 mg/ml AAG to EC50 for Hepatitis C virus in presence of 10% FCS
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.85 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501849 | SIMEPREVIR | 4.0 | 1 | 8.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501849 | SIMEPREVIR | EC50 | = | 1.4 | nM | 8.85 |