Assay Detail
Binding
CHEMBL1673909
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Inhibition of porcine kidney leucyl aminopeptidase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Chemical target validation studies of aminopeptidase in malaria parasites using alpha-aminoalkylphosphonate and phosphonopeptide inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 6.01 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1090914 | — | — | 1 | 6.85 |
| CHEMBL1673064 | — | — | 1 | 6.68 |
| CHEMBL288165 | — | — | 1 | 6.64 |
| CHEMBL1673065 | — | — | 1 | 6.48 |
| CHEMBL1673062 | — | — | 1 | 6.12 |
| CHEMBL1673081 | — | — | 1 | 5.16 |
| CHEMBL1673067 | — | — | 1 | 5.10 |
| CHEMBL1673060 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1090914 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL1673064 | — | Ki | = | 210.0 | nM | 6.68 |
| CHEMBL288165 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL1673065 | — | Ki | = | 330.0 | nM | 6.48 |
| CHEMBL1673062 | — | Ki | = | 750.0 | nM | 6.12 |
| CHEMBL1673081 | — | Ki | = | 6960.0 | nM | 5.16 |
| CHEMBL1673067 | — | Ki | = | 7890.0 | nM | 5.10 |
| CHEMBL1673060 | — | Ki | = | 9570.0 | nM | 5.02 |