Assay Detail
Binding
CHEMBL1675932
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HCV 1b isolate con1 NS3/4A protease using RetS1 as a substrate by fluorescence resonance energy transfer cleavage assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepatitis C virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 9.40 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501849 | SIMEPREVIR | 4.0 | 1 | 9.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501849 | SIMEPREVIR | Ki | = | 0.4 | nM | 9.40 |