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Assay Detail

CHEMBL1676067

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Functional
Antiviral activity against adamantane-, oseltamivir-, zanamivir-susceptible Influenza A virus (A/Ann Arbor/6/1960(H2N2)) infected in MDCK cells assessed as inhibition of viral replication after 3 days by microscopic analysis using crystal violet stain
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus (A/Ann Arbor/6/1960(H2N2))
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

In vitro antiviral activity of favipiravir (T-705) against drug-resistant influenza and 2009 A(H1N1) viruses.
Sleeman K, Mishin VP, Deyde VM, Furuta Y, Klimov AI, Gubareva LV.
Antimicrob Agents Chemother (2010) 54 : 2517 -2524
PubMed 20350949 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.42 6.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL221722 FAVIPIRAVIR 4.0 1 6.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL221722 FAVIPIRAVIR EC50 = 380.0 nM 6.42