Assay Detail
Functional
CHEMBL1676106
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition in human HeLa cells after 72 hrs by trypan blue assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Benzoquinazoline derivatives as new agents affecting DNA processing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.97 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43 | AMSACRINE | 4.0 | 1 | 7.92 |
| CHEMBL123 | ELLIPTECINE | — | 1 | 6.51 |
| CHEMBL1671913 | — | — | 1 | 4.80 |
| CHEMBL1671998 | — | — | 1 | 4.63 |
| CHEMBL1671911 | — | — | 1 | - |
| CHEMBL1671912 | — | — | 1 | - |
| CHEMBL1671914 | — | — | 1 | - |
| CHEMBL1671915 | — | — | 1 | - |
| CHEMBL1671999 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43 | AMSACRINE | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL123 | ELLIPTECINE | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL1671913 | — | IC50 | = | 15700.0 | nM | 4.80 |
| CHEMBL1671998 | — | IC50 | = | 23200.0 | nM | 4.63 |
| CHEMBL1671911 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1671912 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1671914 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1671915 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1671999 | — | IC50 | > | 100000.0 | nM | - |