Assay Detail
Functional
CHEMBL1676122
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Cytotoxicity against human HFF after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, anticancer activity, and iron affinity of the Actinoplanes metabolite 7,8-dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.38 | 4.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672001 | — | — | 1 | 4.51 |
| CHEMBL1672002 | THYMOQUINONE | 2.0 | 1 | 4.48 |
| CHEMBL1672000 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672001 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL1672002 | THYMOQUINONE | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL1672000 | — | IC50 | = | 69000.0 | nM | 4.16 |