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Assay Detail

CHEMBL1676762

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Induction of apoptosis in human chemosensitive MUTU-I cells assessed as formation of apoptotic bodies by propidium iodide FACS analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MUTU-I
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.
McNamara YM, Cloonan SM, Knox AJ, Keating JJ, Butler SG, Peters GH, Meegan MJ, Williams DC.
Bioorg Med Chem (2011) 19 : 1328 -1348
PubMed 21227702 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.89 4.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1165775 1 4.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1165775 EC50 = 13000.0 nM 4.89