Assay Detail
Binding
CHEMBL1679229
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant MKP3 expressed in Escherichia coli
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Dual specificity protein phosphatase 6 (CHEMBL1250381) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.40 | 4.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672293 | — | — | 1 | 4.50 |
| CHEMBL1672294 | — | — | 1 | 4.41 |
| CHEMBL1672291 | — | — | 1 | 4.38 |
| CHEMBL1672295 | — | — | 1 | 4.30 |
| CHEMBL1672292 | — | — | 1 | - |
| CHEMBL1672296 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672293 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL1672294 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL1672291 | — | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL1672295 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL1672292 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL1672296 | — | IC50 | > | 50000.0 | nM | - |