Assay Detail
Binding
CHEMBL1680107
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Displacement of [3H]domperidone from rat cloned dopamine D3 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and Evaluation of Fluorinated Aporphines: Potential Positron Emission Tomography Ligands for D2 Receptors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.57 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672309 | — | — | 1 | 7.00 |
| CHEMBL1672311 | — | — | 1 | 6.62 |
| CHEMBL1672310 | — | — | 1 | 6.39 |
| CHEMBL1672312 | — | — | 1 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672309 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL1672311 | — | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL1672310 | — | Ki | = | 410.0 | nM | 6.39 |
| CHEMBL1672312 | — | Ki | = | 550.0 | nM | 6.26 |