Assay Detail
Binding
CHEMBL1680289
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human ERG
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-gated inwardly rectifying potassium channel KCNH2 (CHEMBL240) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.31 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672352 | — | — | 1 | 5.38 |
| CHEMBL1672351 | — | — | 1 | 5.23 |
| CHEMBL1672354 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672352 | — | Ki | = | 4200.0 | nM | 5.38 |
| CHEMBL1672351 | — | Ki | = | 5900.0 | nM | 5.23 |
| CHEMBL1672354 | — | Ki | > | 8000.0 | nM | - |