Assay Detail
Binding
CHEMBL1680297
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]Bag-3 from mouse BRS-3
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.27 | 8.27 |
| Ki | 1 | 8.80 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672354 | — | — | 2 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672354 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL1672354 | — | IC50 | = | 5.4 | nM | 8.27 |