Assay Detail
Functional
CHEMBL1680828
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity against rat P2X2 receptor expressed in Xenopus laevis oocyte assessed as maximum alpha, beta-meATP-induced inward current by two-electrode voltage-clamp electrophysiology in presence of 10 uM ATP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.31 | 6.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672101 | — | — | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672101 | — | EC50 | = | 489.0 | nM | 6.31 |