Assay Detail
Functional
CHEMBL1680932
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human GPR109b
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.24 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1671877 | — | — | 1 | 6.52 |
| CHEMBL1672639 | — | — | 1 | 5.95 |
| CHEMBL573 | NIACIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1671877 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1672639 | — | EC50 | = | 1120.0 | nM | 5.95 |
| CHEMBL573 | NIACIN | EC50 | > | 10000.0 | nM | - |