Assay Detail
Functional
CHEMBL1680937
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at dog GPR109a
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Canis lupus familiaris |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.37 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1671877 | — | — | 1 | 7.68 |
| CHEMBL573 | NIACIN | 4.0 | 1 | 7.52 |
| CHEMBL1672639 | — | — | 1 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1671877 | — | EC50 | = | 21.0 | nM | 7.68 |
| CHEMBL573 | NIACIN | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1672639 | — | EC50 | = | 126.0 | nM | 6.90 |