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Assay Detail

CHEMBL1685382

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human ERG by patch clamp assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors.
Atkinson KA, Beretta EE, Brown JA, Castrodad M, Chen Y, Cosgrove JM, Du P, Litchfield J, Makowski M, Martin K, McLellan TJ, Neagu C, Perry DA, Piotrowski DW, Steppan CM, Trilles R.
Bioorg Med Chem Lett (2011) 21 : 1621 -1625
PubMed 21324691 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.54 4.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1683577 1 4.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1683577 IC50 = 28900.0 nM 4.54