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Assay Detail

CHEMBL1685456

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Huprines as a new family of dual acting trypanocidal-antiplasmodial agents.
Defaux J, Sala M, Formosa X, Galdeano C, Taylor MC, Alobaid WA, Kelly JM, Wright CW, Camps P, Muñoz-Torrero D.
Bioorg Med Chem (2011) 19 : 1702 -1707
PubMed 21315611 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.19 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1684453 1 5.22
CHEMBL1684455 1 5.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1684453 IC50 = 5990.0 nM 5.22
CHEMBL1684455 IC50 = 7120.0 nM 5.15