Assay Detail
Functional
CHEMBL1686897
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at 5-oxo-ETE receptor in human neutrophils assessed as stimulation of ca2+ mobilization
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
5-oxo-15-HETE: total synthesis and bioactivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.70 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18028 | 5-OXO-ETE | — | 1 | 8.15 |
| CHEMBL1682258 | — | — | 1 | 7.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18028 | 5-OXO-ETE | EC50 | = | 7.0 | nM | 8.15 |
| CHEMBL1682258 | — | EC50 | = | 56.0 | nM | 7.25 |