Assay Detail

CHEMBL1690211

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Binding

Inhibition of human phosphodiesterase 4

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.

Corbau R, Mori J, Phillips C, Fishburn L, Martin A, Mowbray C, Panton W, Smith-Burchnell C, Thornberry A, Ringrose H, Knöchel T, Irving S, Westby M, Wood A, Perros M.
Antimicrob Agents Chemother (2010) 54 : 4451 -4463
PubMed 20660667 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.52	5.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL571987	LERSIVIRINE	2.0	1	5.52

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL571987	LERSIVIRINE	IC50	=	3000.0	nM	5.52