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Assay Detail

CHEMBL1693308

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Pdr5p-dependent UTPase activity in Saccharomyces cerevisiae AD124567 assessed as release of inorganic phosphate after 60 mins by Lineweaver-Burk plot
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Oroidin inhibits the activity of the multidrug resistance target Pdr5p from yeast plasma membranes.
da Silva FR, Tessis AC, Ferreira PF, Rangel LP, Garcia-Gomes AS, Pereira FR, Berlinck RG, Muricy G, Ferreira-Pereira A.
J Nat Prod (2011) 74 : 279 -282
PubMed 21207971 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.89 4.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL397591 OROIDIN 1 4.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL397591 OROIDIN IC50 = 13000.0 nM 4.89