Assay Detail
Functional
CHEMBL1694204
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Antimalarial activity against chloroquine-resistant Plasmodium falciparum Dd2 assessed as inhibition of [3H]hypoxanthine incorporation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and P. vivax.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.45 | 7.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL221655 | — | — | 1 | 7.48 |
| CHEMBL220692 | — | — | 1 | 7.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL221655 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL220692 | — | IC50 | = | 39.0 | nM | 7.41 |