Assay Detail
Binding
CHEMBL1694673
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum glutathione S-transferase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glutathione S-transferase (CHEMBL1697656) ↗| Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
Publication
Compounds structurally related to ellagic acid show improved antiplasmodial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.61 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1688544 | CORULEOELLAGIC ACID | — | 1 | 5.16 |
| CHEMBL1688543 | FLAVELLAGIC ACID | — | 1 | 4.53 |
| CHEMBL6246 | ELLAGIC ACID | 2.0 | 1 | 4.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1688544 | CORULEOELLAGIC ACID | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL1688543 | FLAVELLAGIC ACID | IC50 | = | 29300.0 | nM | 4.53 |
| CHEMBL6246 | ELLAGIC ACID | IC50 | = | 74400.0 | nM | 4.13 |