Assay Detail
Functional
CHEMBL1738017
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Luminescence Cell Based Dose Confirmation HTS to Identify Activators of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1813, AID1829]
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Category | confirmatory |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.04 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1369984 | — | — | 1 | 5.70 |
| CHEMBL1728581 | — | — | 1 | 5.41 |
| CHEMBL1722092 | — | — | 1 | 4.92 |
| CHEMBL1708923 | — | — | 1 | 4.13 |
| CHEMBL1709314 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1369984 | — | EC50 | = | 2016.0 | nM | 5.70 |
| CHEMBL1728581 | — | EC50 | = | 3922.0 | nM | 5.41 |
| CHEMBL1722092 | — | EC50 | = | 12010.0 | nM | 4.92 |
| CHEMBL1708923 | — | EC50 | = | 73500.0 | nM | 4.13 |
| CHEMBL1709314 | — | EC50 | > | 195000.0 | nM | - |