Assay Detail
Unclassified
CHEMBL1738360
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Family selectivity: Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1792, AID1796, AID1823, AID2532, AID2538, AID2539, AID2541, AID2545, AID2556, AID2664, AID2752, AID2773, AID2808, AID2819, AID434953, AID434974, AID434997, AID463255, AID488778, AID504381, AID504410] Panel member name: NOX3 Selectivity
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Unclassified |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.11 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL407734 | — | — | 1 | 5.52 |
| CHEMBL541018 | — | — | 1 | 5.12 |
| CHEMBL1517979 | — | — | 1 | 4.70 |
| CHEMBL1315444 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL407734 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL541018 | — | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL1517979 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL1315444 | — | IC50 | > | 50000.0 | nM | - |