Assay Detail
Functional
CHEMBL1738404
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyces cerevisiae, specifically LAP4. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1873, AID1908, AID2023, AID2271, AID2621, AID2745, AID2757]
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Saccharomyces cerevisiae |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Vacuolar aminopeptidase 1 (CHEMBL1741175) ↗| Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 5.27 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224325 | CHLORQUINALDOL | 2.0 | 1 | 5.27 |
| CHEMBL1582355 | — | — | 1 | - |
| CHEMBL225164 | CLOXYQUIN | 2.0 | 1 | - |
| CHEMBL1343773 | — | — | 1 | - |
| CHEMBL1509065 | — | — | 1 | - |
| CHEMBL1449204 | — | — | 1 | - |
| CHEMBL1515267 | — | — | 1 | - |
| CHEMBL1305644 | — | — | 1 | - |
| CHEMBL1590579 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224325 | CHLORQUINALDOL | EC50 | = | 5385.0 | nM | 5.27 |
| CHEMBL1582355 | — | EC50 | 37310.0 | nM | - | |
| CHEMBL225164 | CLOXYQUIN | EC50 | 207800.0 | nM | - | |
| CHEMBL1343773 | — | EC50 | 35850.0 | nM | - | |
| CHEMBL1509065 | — | EC50 | 79640.0 | nM | - | |
| CHEMBL1449204 | — | EC50 | 41210.0 | nM | - | |
| CHEMBL1515267 | — | EC50 | 104700.0 | nM | - | |
| CHEMBL1305644 | — | EC50 | 86410.0 | nM | - | |
| CHEMBL1590579 | — | EC50 | 35350.0 | nM | - |