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Assay Detail

CHEMBL1738515

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Unclassified
PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identify inhibitors of Retinoblastoma Binding Protein 9 (RBBP9): Gel-based Activity-Based Protein Profiling (ABPP) IC50. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1515, AID1537, AID1790, AID2299] Panel member name: Panel member description: RBBP9 IC50 Gel-based ABPP Assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Unclassified
Category confirmatory
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Serine hydrolase RBBP9 (CHEMBL1075121)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.50 6.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1092791 1 6.20
CHEMBL1093346 1 5.72
CHEMBL1092116 1 5.30
CHEMBL1092376 1 5.24
CHEMBL1092114 1 5.04
CHEMBL1092816 1 -
CHEMBL1092115 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1092791 IC50 = 635.0 nM 6.20
CHEMBL1093346 IC50 = 1900.0 nM 5.72
CHEMBL1092116 IC50 = 5000.0 nM 5.30
CHEMBL1092376 IC50 = 5700.0 nM 5.24
CHEMBL1092114 IC50 = 9100.0 nM 5.04
CHEMBL1092816 IC50 = 1500000.0 nM -
CHEMBL1092115 IC50 = 1200000.0 nM -