Assay Detail
Unclassified
CHEMBL1738688
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Late stage results from the probe development efforts to identify inhibitors of Matrix Metalloprotease-13 (MMP-13). (Class of assay: screening) [Related pubchem assays (depositor defined):AID1931, AID570, AID734, AID735, AID769] Panel member name: MMP-13 [IC50 Assay]
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Unclassified |
| Category | screening |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.54 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1371684 | — | — | 1 | 5.61 |
| CHEMBL1515648 | — | — | 1 | 5.55 |
| CHEMBL473326 | — | — | 1 | 5.47 |
| CHEMBL1736529 | — | — | 1 | - |
| CHEMBL1708633 | — | — | 1 | - |
| CHEMBL1717700 | — | — | 1 | - |
| CHEMBL1566001 | — | — | 1 | - |
| CHEMBL1720056 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1371684 | — | IC50 | = | 2437.0 | nM | 5.61 |
| CHEMBL1515648 | — | IC50 | = | 2819.0 | nM | 5.55 |
| CHEMBL473326 | — | IC50 | = | 3357.0 | nM | 5.47 |
| CHEMBL1736529 | — | IC50 | > | 39840.0 | nM | - |
| CHEMBL1708633 | — | IC50 | > | 39840.0 | nM | - |
| CHEMBL1717700 | — | IC50 | > | 39840.0 | nM | - |
| CHEMBL1566001 | — | IC50 | > | 39840.0 | nM | - |
| CHEMBL1720056 | — | IC50 | > | 39840.0 | nM | - |