Assay Detail
Binding
CHEMBL1763486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mushroom tyrosinase using L-tyrosine as a substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of hydroxy substituted phenyl-benzo[d]thiazole analogues for antityrosinase activity in B16 cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.22 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1408767 | — | — | 1 | 8.00 |
| CHEMBL47875 | — | — | 1 | 5.94 |
| CHEMBL287556 | KOJIC ACID | — | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1408767 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL47875 | — | IC50 | = | 1140.0 | nM | 5.94 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 18450.0 | nM | 4.73 |