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Assay Detail

CHEMBL1763495

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mushroom tyrosinase at 20 uM by Lineweaver-Burk plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Agaricus bisporus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tyrosinase (CHEMBL3318)
Type SINGLE PROTEIN
Organism Agaricus bisporus

Publication

Synthesis and biological activity of hydroxy substituted phenyl-benzo[d]thiazole analogues for antityrosinase activity in B16 cells.
Ha YM, Park JY, Park YJ, Park D, Choi YJ, Kim JM, Lee EK, Han YK, Kim JA, Lee JY, Moon HR, Chung HY.
Bioorg Med Chem Lett (2011) 21 : 2445 -2449
PubMed 21397499 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.44 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL47875 1 5.77
CHEMBL1408767 1 5.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL47875 Ki = 1700.0 nM 5.77
CHEMBL1408767 Ki = 7700.0 nM 5.11