Assay Detail
Functional
CHEMBL1763558
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Antiproliferative activity against human MCF7 cells at 10 uM after 72 hrs by MTS assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Impact of aryloxy-linked quinazolines: a novel series of selective VEGFR-2 receptor tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.22 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1761933 | — | — | 1 | 5.82 |
| CHEMBL29197 | — | — | 1 | 5.33 |
| CHEMBL301018 | — | — | 1 | 5.31 |
| CHEMBL1761938 | — | — | 1 | 5.19 |
| CHEMBL1761942 | — | — | 1 | 5.17 |
| CHEMBL1761934 | — | — | 1 | 5.15 |
| CHEMBL1761944 | — | — | 1 | 5.11 |
| CHEMBL447230 | — | — | 1 | 5.04 |
| CHEMBL1278235 | — | — | 1 | 5.03 |
| CHEMBL1761940 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1761933 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL29197 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL301018 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL1761938 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL1761942 | — | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL1761934 | — | IC50 | = | 7150.0 | nM | 5.15 |
| CHEMBL1761944 | — | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL447230 | — | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL1278235 | — | IC50 | = | 9450.0 | nM | 5.03 |
| CHEMBL1761940 | — | IC50 | = | 9800.0 | nM | 5.01 |