Assay Detail
Functional
CHEMBL1764428
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Desensitization of 5-oxo-ETE receptor in indo-1-labeled human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
C20-trifluoro-5-oxo-ETE: a metabolically stable 5-oxo-ETE derivative.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.32 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18028 | 5-OXO-ETE | — | 1 | 8.52 |
| CHEMBL1760545 | — | — | 1 | 8.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18028 | 5-OXO-ETE | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL1760545 | — | IC50 | = | 7.5 | nM | 8.12 |