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Assay Detail

CHEMBL1767770

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Functional
Antiparasitic activity against Toxoplasma gondii assessed as growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Toxoplasma gondii
Confidence 1 — Organism
Curated By Autocuration

Target

Toxoplasma gondii (CHEMBL612888)
Type ORGANISM
Organism Toxoplasma gondii

Publication

Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.
Rosso VS, Szajnman SH, Malayil L, Galizzi M, Moreno SN, Docampo R, Rodriguez JB.
Bioorg Med Chem (2011) 19 : 2211 -2217
PubMed 21419634 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.03 5.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259192 1 5.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259192 IC50 = 9370.0 nM 5.03