Assay Detail
Binding
CHEMBL1768626
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DDP4 at pH 7.4 preincubated for 10 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Pro-soft Val-boroPro: a strategy for enhancing in vivo performance of boronic acid inhibitors of serine proteases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.00 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1765235 | — | — | 1 | 8.15 |
| CHEMBL1765234 | — | — | 1 | 7.72 |
| CHEMBL67279 | TALABOSTAT | 3.0 | 1 | 6.33 |
| CHEMBL63860 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1765235 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL1765234 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL67279 | TALABOSTAT | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL63860 | — | IC50 | = | 1600.0 | nM | 5.80 |