Assay Detail
Functional
CHEMBL1769978
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Cytotoxicity against mouse B16F10 cells harboring BRAF V600F mutation assessed as cell viability by MTS assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16-F10 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic oleanane-type saponins from Albizia inundata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.25 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1765593 | — | — | 1 | 5.33 |
| CHEMBL1765595 | — | — | 1 | 5.29 |
| CHEMBL1765597 | — | — | 1 | 5.20 |
| CHEMBL1765596 | PITHEDULOSIDE C | — | 1 | 5.16 |
| CHEMBL1765594 | — | — | 1 | - |
| CHEMBL509569 | PROSAPOGENIN 4 | — | 1 | - |
| CHEMBL504527 | ACUTOSIDE A | — | 1 | - |
| CHEMBL1765591 | — | — | 1 | - |
| CHEMBL1765592 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1765593 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL1765595 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL1765597 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL1765596 | PITHEDULOSIDE C | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL1765594 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL509569 | PROSAPOGENIN 4 | IC50 | > | 20000.0 | nM | - |
| CHEMBL504527 | ACUTOSIDE A | IC50 | > | 20000.0 | nM | - |
| CHEMBL1765591 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1765592 | — | IC50 | > | 20000.0 | nM | - |