Assay Detail
Binding
CHEMBL1772169
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to amyloid beta 1 to 40
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Arylimidazo[2,1-b]benzothiazoles: a new family of amyloid binding agents with potential for PET and SPECT imaging of Alzheimer's brain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL207456 | PITTSBURGH COMPOUND B | 2.0 | 1 | 8.00 |
| CHEMBL599472 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL207456 | PITTSBURGH COMPOUND B | Kd | = | 10.0 | nM | 8.00 |
| CHEMBL599472 | — | Kd | = | 10.0 | nM | 8.00 |