Assay Detail
Functional
CHEMBL1772804
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Cytotoxicity against human SGC7901 after 48 hrs by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SGC-7901 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and synthesis of N-phenylacetyl (sulfonyl) 4,5-dihydropyrazole derivatives as potential antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.33 | 4.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1770486 | — | — | 1 | 4.67 |
| CHEMBL1770490 | — | — | 1 | 4.57 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.50 |
| CHEMBL1770487 | — | — | 1 | 4.29 |
| CHEMBL1770495 | — | — | 1 | 4.28 |
| CHEMBL1770493 | — | — | 1 | 4.18 |
| CHEMBL1770494 | — | — | 1 | 4.13 |
| CHEMBL1770489 | — | — | 1 | 4.01 |
| CHEMBL1770488 | — | — | 1 | - |
| CHEMBL1770491 | — | — | 1 | - |
| CHEMBL1770492 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1770486 | — | IC50 | = | 21230.0 | nM | 4.67 |
| CHEMBL1770490 | — | IC50 | = | 26830.0 | nM | 4.57 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 31460.0 | nM | 4.50 |
| CHEMBL1770487 | — | IC50 | = | 51480.0 | nM | 4.29 |
| CHEMBL1770495 | — | IC50 | = | 52820.0 | nM | 4.28 |
| CHEMBL1770493 | — | IC50 | = | 66400.0 | nM | 4.18 |
| CHEMBL1770494 | — | IC50 | = | 73640.0 | nM | 4.13 |
| CHEMBL1770489 | — | IC50 | = | 97260.0 | nM | 4.01 |
| CHEMBL1770488 | — | IC50 | = | 103770.0 | nM | - |
| CHEMBL1770491 | — | IC50 | = | 103020.0 | nM | - |
| CHEMBL1770492 | — | IC50 | = | 149810.0 | nM | - |