Assay Detail
Binding
CHEMBL1775262
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Inhibition of JNK1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.52 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1773329 | — | — | 1 | 6.32 |
| CHEMBL1773334 | — | — | 1 | 4.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1773329 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL1773334 | — | IC50 | = | 19730.0 | nM | 4.71 |