Assay Detail
Functional
CHEMBL1775502
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Antiviral activity against Hepatitis C virus infected in human Ava5 cells expressing EG(delta4AB)SEAP reporter gene assessed as decreased viral replication measured as SEAP activity by Phospha-Light assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Ava5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| EC50 | 1 | 5.42 | 5.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL412437 | DISOGENIN | — | 2 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL412437 | DISOGENIN | EC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL412437 | DISOGENIN | Activity | - | — | - |