Assay Detail
Functional
CHEMBL1775529
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Antiparasitic activity against yellow fluorescent protein expressing Toxoplasma gondii 2F-1 infected in HFF treated 6 hrs after infection measured after 48 hrs
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Chemistry and biology of macrolide antiparasitic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.93 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1773086 | — | — | 1 | 5.10 |
| CHEMBL1774292 | — | — | 1 | 5.05 |
| CHEMBL1774451 | — | — | 1 | 5.05 |
| CHEMBL1774452 | — | — | 1 | 5.05 |
| CHEMBL1774297 | — | — | 1 | 5.00 |
| CHEMBL1774453 | — | — | 1 | 4.92 |
| CHEMBL529 | AZITHROMYCIN | 4.0 | 1 | 4.36 |
| CHEMBL1774304 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1773086 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL1774292 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL1774451 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL1774452 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL1774297 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1774453 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL529 | AZITHROMYCIN | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL1774304 | — | IC50 | > | 10000.0 | nM | - |