Assay Detail
Functional
CHEMBL1776104
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Antiviral activity against Human cytomegalovirus (strain AD169) infected in human HFF cells assessed inhibition of viral replication after 1 hr by plaque reduction assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Broad-spectrum antiviral activity including human immunodeficiency and hepatitis C viruses mediated by a novel retinoid thiosemicarbazone derivative.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC90 | 1 | - | - |
| EC50 | 1 | 5.62 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1774258 | — | — | 2 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1774258 | — | EC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL1774258 | — | EC90 | > | 4.0 | uM | - |