Assay Detail
Functional
CHEMBL1776232
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Cytotoxicity against drug-sensitive human K562 cells after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. Part 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.04 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1775214 | — | — | 1 | 7.07 |
| CHEMBL1775215 | — | — | 1 | 7.06 |
| CHEMBL1775213 | — | — | 1 | 7.02 |
| CHEMBL153529 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1775214 | — | IC50 | = | 86.0 | nM | 7.07 |
| CHEMBL1775215 | — | IC50 | = | 88.0 | nM | 7.06 |
| CHEMBL1775213 | — | IC50 | = | 96.0 | nM | 7.02 |
| CHEMBL153529 | — | IC50 | = | 100.0 | nM | 7.00 |