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Assay Detail

CHEMBL1776276

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of yeast alpha-glucosidase assessed as p-nitrophenol release after 20 mins by microplate spectrophotometer
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds.
Chan HH, Hwang TL, Reddy MV, Li DT, Qian K, Bastow KF, Lee KH, Wu TS.
J Nat Prod (2011) 74 : 796 -802
PubMed 21417387 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.21 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL168 OLEANOLIC_ACID 1 4.30
CHEMBL510111 1 4.12
CHEMBL404271 ACARBOSE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL168 OLEANOLIC_ACID IC50 = 50400.0 nM 4.30
CHEMBL510111 IC50 = 75000.0 nM 4.12
CHEMBL404271 ACARBOSE IC50 = 678000.0 nM -