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Assay Detail

CHEMBL1781216

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Binding
Inhibition of JNK2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 9 (CHEMBL4179)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: design and development to a highly selective lead.
Soth M, Abbot S, Abubakari A, Arora N, Arzeno H, Billedeau R, Dewdney N, Durkin K, Frauchiger S, Ghate M, Goldstein DM, Hill RJ, Kuglstatter A, Li F, Loe B, McCaleb K, McIntosh J, Papp E, Park J, Stahl M, Sung ML, Suttman R, Swinney DC, Weller P, Wong B, Zecic H, Gabriel T.
Bioorg Med Chem Lett (2011) 21 : 3452 -3456
PubMed 21515047 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.80 7.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1232769 1 7.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1232769 Kd = 16.0 nM 7.80